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A study has examined the risk of atrial fibrillation ( AF ) at the time of first diagnosis of gout compared with matched controls and has followed incident gout patients and their matched controls aft ...


The aim of a study was to investigate the prevalence of monosodium urate ( MSU ) crystal deposits, indicative for gout, in a population of rheumatoid arthritis ( RA ) patients with concomitant hyperur ...


Previous studies of stroke in systemic lupus erythematosus ( SLE ) have had limited statistical power, combined stroke subtypes into composite outcomes, and lacked a reference population estimate. T ...


A study has estimated the frequency of cardiovascular events that occurred after diagnosis in a large Spanish cohort of patients with systemic lupus erythematosus ( SLE ) and has investigated the main ...


The aim was to study the association between 25-hydroxyvitamin D [ 25(OH)D ] levels and the clinical characteristics of patients with chronic inflammatory rheumatic diseases ( CIRD ). Researchers s ...


A study has described the long-term adherence, efficacy, and safety in patients with psoriatic arthritis ( PsA ) treated with Etanercept ( Enbrel ) in a daily clinical setting in Belgium. The PROVE ...


Interleukin-17A ( IL-17A ) is a key cytokine in the pathogenesis of psoriatic disease of the skin and joints. In phase 3 trials, Secukinumab ( Cosentyx ), a fully human anti-IL-17A monoclonal antibody ...


Since the publication of the European League Against Rheumatism ( EULAR ) recommendations for the pharmacological treatment of psoriatic arthritis ( PsA ) in 2012, new evidence and new therapeutic age ...


Most incident cases of psoriatic arthritis ( PsA ) present among patients with pre-existing psoriasis, and because of the high absolute prevalence of psoriatic arthritis among psoriasis patients this ...


Patients with rheumatoid arthritis ( RA ) and co-existent bronchiectasis ( BRRA ) have a five-fold increased mortality compared to rheumatoid arthritis alone. Yet previous studies have found no differ ...


Positive data from the phase IIb BALANCE-I and BALANCE-II trials for experimental JAK1 inhibitor, ABT-494 in rheumatoid arthritis were announced. The BALANCE-I study evaluated one of four twice-da ...


Stimulators of the soluble guanylate cyclase ( sGC ) have recently been shown to inhibit transforming growth factor-beta ( TGF-beta ) signalling. Researchers aimed to demonstrate that Riociguat ( ...


Enhanced cardiovascular risk in ankylosing spondylitis provides a strong rationale for early therapeutical intervention. In view of the proven benefit of statins in atherosclerotic vascular disease, a ...


Patients with rheumatoid arthritis and carotid artery plaques have increased risk of acute coronary syndromes. Statin treatment with low density lipoprotein cholesterol ( LDL-c ) goal  less than or eq ...


The objective of a study was to determine the safety of Ocrelizumab in patients with rheumatoid arthritis. An analysis of the double-blind, placebo-controlled periods and long-term follow-up of 4 O ...